Spain are, once again, playing without a real striker. They're also not playing with two obvious pivot midfielders or three obvious central midfielders, so Cesc Fabregas isn't a lock to play as the "false nine". He looks more likely to play in the midfield, based on this selection. Juan Mata, Pedro or Santi Cazorla look like they're getting a run in the role. Carles Puyol returns to the team, alongside Sergio Ramos, and Victor Valdes starts in goal in the absence of Iker Casillas.
Uruguay's team shape isn't entirely obvious either, but it looks like a 4-4-2. Don't be shocked if they switch to a back three, with Nicolas Lodeiro moving farther forward and Christian Rodriguez operating as a left wingback.
Uruguay starting lineup (4-4-2): Fernando Muslera; Martin Caceres, Diego Lugano, Diego Godin, Maxi Pereira; Nicolas Lodeiro, Alvaro Gonzalez, Diego Perez, Christian Rodriguez, Edinson Cavani, Luis Suarez