Xavi Hernandez is fit for Barcelona, but Carles Puyol has dropped out of their lineup with an injury. Javier Mascherano steps into the Barcelona defense. Cesc Fabregas has been left on the bench, while Andres Iniesta will play in the center instead of on the wing. David Villa and Pedro Rodriguez flank Lionel Messi for the Blaugrana.
For AC Milan, if it's not broke, why fix it? They've made a couple of changes due to changes in fitness, but they're using more or less the same team that won at San Siro. The now-fit Mathieu Flamini enters for Sulley Muntari, while M'Baye Niang plays in place of the injured Giampaolo Pazzini. Niang, El Shaarawy and Boateng have all primarily played wide in Massimilliano Allegri's 4-3-3, so it will be interesting to see who plays center forward.
AC Milan lineup (4-3-3): Christian Abbiati; Kevin Constant, Philippe Mexes, Cristian Zapata, Ignazio Abate; Mathieu Flamini, Massimo Ambrosini, Riccardo Montolivo; Stephan El Shaarawy, M'Baye Niang, Kevin Prince-Boateng
Kickoff is at 3:45 p.m. ET, 8:45 p.m. local time from the Camp Nou. You can catch the game on FOX Soccer in the U.S. and ITV 1 in the U.K.