Paris Saint-Germain will look to preserve their 2-1 lead over Valencia as the two sides meet in Paris, but will have to do so without talismanic striker Zlatan Ibrahimovic.
The Parisians gained two away goals which could prove vital thanks to Argentinian duo Ezequiel Lavezzi and Javier Pastore, although the performance was marred by Ibrahimovic's red card at the end of the game. Combined with a recent stutter in the league, suffering a shock 1-0 defeat at the hands of Reims, there is still much for the hosts to be wary about.
Valencia, meanwhile, have a slim hope but will need to score at least two goals to see them through. They will need to make the most of Roberto Soldado, who has been enduring a goal drought in European competition stretching back to November, but could be key to scoring the goals they require. Although with the visitors being forced to field a makeshift defence, they may end up requiring more than a pair of goals to see them through.
Paris Saint-Germain injuries and suspensions
Out: Zlatan Ibrahimovic (suspended), Marco Verratti (suspended).
Valencia injuries and suspensions
Paris Saint-Germain will have to make do without their star striker Zlatan Ibrahimovic after he received a sending-off at the end of the first leg. He will serve the first of a two-match suspension, with Marco Verratti also missing out with a one-game ban.
Valencia will have injury problems in defence with Adil Rami and Ricardo Costa out. Jeremy Mathieu is set to continue as a makeshift central defender in their absence.
Match Date\Time: 8:45 p.m. local, 7:45 p.m. BST, 2:45 p.m. ET
Venue: Parc des Princes, Paris, France
TV: FOX Soccer (U.S. English), FOX Deportes (U.S. Spanish), Sky Sports 4 (U.K.), Sportsnet Regional (Canada), Canal+ (France), C+ Liga de Campeones (Spain)
Online: FOX Soccer 2Go (U.S.)