The Blues fielded a full-strength side for their clash against City and may rotate players as they face a tricky run-in and a buildup of fixtures with the team still fighting in the Europa League. Fulham, meanwhile, have no such concerns, although complacency could set in as Martin Jol's men appear to have little to play for.
Chelsea have no new injury problems, but their squad will be stretched to the limit, which will give the Cottagers hope. It may not be the fiercest of rivalries, but the scalp would still be worth much to them.
Fulham injuries and suspensions
Chelsea injuries and suspensions
Fulham have no new injury problems but are unlikely to be welcoming back Diarra or Duff, while Dejagah will be out for the season.
Chelsea are still not ready to return defensive duo Cole and Cahill to the fray, but have no further problems.
Match Date\Time: Wednesday, 8 p.m. local, 3 p.m. ET
Venue: Craven Cottage, London, England
TV: FOX Deportes (U.S. Spanish), FOX Soccer Channel (U.S. English)