Uruguay sit fifth in CONMEBOL World Cup qualifying, in reach of an automatic qualifying spot, but they're up against a difficult test on Tuesday. They'll be underdogs at home against Colombia, thanks to the injuries and suspensions that have ravaged their back line.
All of Diego Godin, Diego Lugano, Sebastian Coates and Martin Caceres are unavailable for Uruguay. While Caceres has played more fullback than central defense in recent years, those are arguably the team's top four center backs. Likely starting in their place is 37-year-old Andres Scotti, who is likely to be paired with an uncapped youngster. Uruguay could also opt to move one of their defensive midfielders, Diego Perez or Sebastián Eguren, back into defense.
Colombia are a bit shorthanded as well, though not as badly as Uruguay. They'll be without Macnelly Torres and Pablo Armero. Depending on how attacking of a lineup Jose Peckerman wants to go with, he could move Juan Cuadrado back to left back, though he hasn't played much in a back four.
Match date/time: Tuesday, 6 p.m. ET
Venue: Centenario, Montevideo, Uruguay
TV: beIN Sport en Español (U.S.)
Online: beIN Sport Play (U.S.)