David Moyes has made the interesting decision to keep Nemanja Vidic, Adnan Januzaj and Marouane Fellaini out of his team, instead inserting Rio Ferdinand, Ryan Giggs and Antonio Valencia into his starting XI for Manchester United's Champions League match against Olympiacos. The Red Devils make one more change from the weekend, though that one is required. Danny Welbeck is in for the cup-tied Juan Mata.
With Michael Olaitan out and Javier Saviola not quite fit, Olympiacos have opted to play without a true center forward. However, both Joel Campbell and Hernan Perez, the starting wingers from the first leg, have played striker before.
Olympiacos lineup (4-2-3-1): Roberto; Jose Holebas, Kostas Manolas, Ivan Marcano, Leandro Salino; Giannis Maniatis, Delvin N'Dinga; Hernan Pérez, Alejandro Dominguez, David Fuster; Joel Campbell
Kickoff is at 7:45 p.m. local time, 3:45 p.m. ET from Old Trafford. You can catch the game on Sky Sports 1 in the UK, FOX Sports 1 in the US and Sportsnet regional networks in Canada.