This look like it hurt a lot, and I'll be stunned if Christoph Kramer doesn't have a broken nose, a concussion, or both.
UPDATE: Kramer left the game and was replaced by Andre Schürrle.
The really bad news for Germany? Kramer was an injury replacement. Sami Khedira was named in the starting XI, but Kramer was put into the team in Khedira's place due to an injury. If they're both hurt, Germany's in serious trouble in midfield.