Inter snapped Juventus' 49-match unbeaten run with victory in November but since then their form has nosedived. They will need a repeat to enhance their slim hopes of Champions League qualification.
Fiorentina did their Champions League qualification hopes no harm with a 3-2 victory over struggling Genoa in Florence.
Champions League-chasing Fiorentina take on relegation-battling Genoa in a match which will be crucial for both teams' seasons.
Fiorentina beat Lazio 2-0 to climb above them in the table and go just three points behind Milan in race for the final Champions League qualification place.
Chievo ran out 2-0 victors over Napoli, crushing their title ambitions in the process. Edinson Cavani had a penalty saved as the Partenopei just couldn't seem to create anything to trouble their opponents.
Chievo take on Napoli in a match between two sides at opposite ends of the table, but in similarly difficult runs of form.
Roma beat Genoa 3-1 in a hugely entertaining encounter with both sides having opportunities to win it.
Torino and Palermo played out a 0-0 draw, doing little to help Palermo's hopes of avoiding relegation.
At half time, Inter were 2-0 down to Catania however the introduction of Rodrigo Palacio changed everything as he scored two and set up one to give Inter a 3-2 comeback victory.
Having both recently changed managers, Roma and Genoa have both been in resurgent form of late, Roma beating Juventus and Atalanta whilst Genoa have gone unbeaten in five and lifted themselves out of the relegation zone.
Gian Piero Gasperini was re-appointed as Palermo manager after a month away and with the club still mired in relegation woes. A potentially tough trip to Torino welcomes him back to the fold.
Torino dominated their match with Atalanta for long periods but struggled to put the game to bed until Valter Birsa popped up three minutes from time to send the points to the home side.
Francesco Totti scored an unstoppable strike to give Roma their first win of 2013 over league leaders Juventus.
In-form Juventus travel to the capital to take on a Roma side in crisis, following their 3-1 loss to Sampdoria last weekend.
Celtic have made the knockout stage of the Champions League for the first time in five years. We take a look back at their previous last 16 encounters to understand how they can progress this time around.
Diego Milito made a triumphant return from injury, getting on the scoresheet as Inter registered only their second win of 2013.
Despite being outplayed in the first half, Sampdoria punished Roma's inability to turn their dominance into goals with an effective second half display that saw them win 3-1. Maybe Zdenek Zeman wasn't the problem at Roma after all.
Following their 3-1 defeat at the hands of lowly Siena last week, Inter are being labelled as a club in crisis. Chievo Verona will look to pile more misery on them following good showings against Lazio and Juventus lately.
Sampdoria welcome Roma to the Luigi Ferraris, with the visitors embarking on a new era following the dismissal of manager Zdenek Zeman.
Siena completed an historic league double over Inter, with a clinical display of counter-attacking ensuring they took all the points with a 3-1 victory.
After beating the Nerazzuri 2-0 at the San Siro earlier in the season, Siena now host Inter having lost seven of their past eight matches. Inter will smell blood and look to exact revenge for their earlier defeat.
Torino and Sampdoria played out a 0-0 draw with both sides failing to recapture any of the cutting edge they had shown he previous week.
An exciting and in-form Torino side invite Sampdoria to the Olimpico di Torino for a mid-table battle, fresh off the back of their pulsating 2-2 draw with Inter last week. Sampdoria beat Pescara 6-0 last time out so this match promises much.
Torino put in a sparkling display at the San Siro but Esteban Cambiasso rescued a point for Inter from a pulsating encounter.
Chievo frustrated a more dominant Lazio side for long periods, before providing a sucker punch in the second half, which proved to be enough for victory.
Inter's inconsistent recent form has left them down and out in the title race and they need to recreate some of their earlier season performances against a resurgent Torino, who haven't lost in five.
After their surprise 2-2 draw with Palermo last weekend, Lazio need to bounce back with a victory against Chievo in order to exert pressure on the league leaders.
A brace from Giampaolo Pazzini sent Milan to a comfortable victory and consigned Bologna to a second consecutive defeat at the San Siro.