The Bills smartly addressed the defense early in the draft, and found two starters in end Shaq Lawson and middle linebacker Reggie Ragland. The Bills needed to get a player on the defensive line who can rush the passer and they got that in Lawson, a player who had 12.5 sacks and 25.5 tackles for a loss in 2015. Washington is a nice rotational player on the defensive line. At Ohio State, he was used over the nose but moved to more of a three-technique in 2015. Washington is NFL-ready as a pass rusher, but he has to get better versus the run. Cardale Jones is the wild card. His tools are off the chart, but he's incredibly inexperienced. In the fifth round the Bills got a good running back In Jonathan Williams. If LeSean McCoy struggles, he can step right into the lineup. The pick of Kolby Listenbee in the sixth round was one of my favorite picks of the draft. He was overshadowed by the force that is Josh Doctson, but he can fly on the field. Let him get vertical in the passing game and get him the ball.
—Dan Kadar, SB Nation
Lawson is coming off of a fantastic 2015 season, his first as a full-time starter, in which he recorded 35 solo tackles, 24.5 tackles for loss, and 12.5 sacks. Ryan and the Bills will count on his ability to slide into the spot vacated by the since-released Mario Williams and continue to produce for a defense that desperately needs a boost in the pass-rushing department. Lawson is a great marriage of value and need, but he will be under a lot of pressure to perform as a 22-year-old rookie this fall.
Perhaps you’ve heard that Ragland is a "two-down thumper" at linebacker in the pre-draft process; the fact that the Bills just traded up for him would seem to indicate that they think otherwise. Time will tell how the team plans on fitting him into a linebacker rotation that also includes veterans Preston Brown and Zach Brown, but the odds are low that the Bills drafted Ragland to ride the pine.
Washington is a 6'3", 301-pound defensive tackle with 34.5-inch arms; he played both end and tackle in his four years with the Buckeyes, and given his sufficient length, it's fair to expect that he'll play both tackle and end in the Ryan brothers' hybrid-front defense, as well.
Jones is, of course, one of the most polarizing players in this year's draft. Standing 6'5" and weighing in at 253 pounds, with an arm that can throw a football 70 yards downfield, Jones is the most physically imposing quarterback available. As a redshirt sophomore, Jones had a heroic run for the 2014 national-champion Buckeyes, rising from the third string after injuries, throwing for 742 yards, five touchdowns, and two interceptions (and adding 90 rushing yards and a touchdown) as Ohio State defeated their remaining opponents.
Williams also fits the profile of a running back that fits into the Greg Roman offense: he's big (5'11", 220 pounds) with enough speed (4.63 seconds in the 40-yard dash with a 1.57-second 10-yard split) and quickness to produce around the line of scrimmage. In Buffalo, he'll add to the depth of a Bills backfield that could be dealing with a LeSean McCoy suspension early in the season, and which also features Karlos Williams, Mike Gillislee, and James Wilder, Jr.
Listenbee, who made a pre-draft visit with the Bills, is a tantalizing athlete coming off of two solid seasons' worth of production as a starter with the Horned Frogs playing opposite of first-round pick Josh Doctson. He's a 6'0", 197-pound wideout with excellent straight-line speed (4.39 seconds in the 40-yard dash at the Combine) and explosion (10'9" in the broad jump) that can win jump balls (35.5-inch vertical jump). In his four-year career at TCU, Listenbee caught 74 passes for 1,432 yards (that's 19.4 yards per reception) and nine touchdowns.
A three-year contributor in the Trojans' defensive backfield, Seymour, a senior entrant in the draft, finished his USC career with 127 tackles, three interceptions, 18 defended passes, and a sack. He possesses more than enough athleticism to interest the Bills this late in the draft, coming in at a half-inch shy of 6'0" and 186 pounds, with 4.39-second 40-yard dash speed (with a 1.55-second 10-yard split), a 10'4" broad jump, and a 35-inch vertical jump.