As you fill out your office pools, the SB Nation Studio crew is here to help you with special regional breakdowns for the 2013 NCAA Tournament. This time, Dan Rubenstein, Nick Hauselman and Rob Manganaro break down Midwest regional action that starts with the top-seeded Louisville Cardinals.
The Cardinals' tremendous guard play and overall talent make them the team to beat, but they face stiff competition from Ryan Kelly and Mason Plumlee at Duke at the No. 2 seed. In addition, Michigan State, Memphis, Oklahoma State and St. Louis all have reasons to believe they can exceed expectations and make the Final Four.
If you're looking for upset possibilities, Oregon is fresh off of a Pac-12 tournament win. In addition, Cincinnati could upend Creighton and Valpo, at No. 14, could be a spoiler. Then again, at this time of year, anything goes. Make sure to watch the Midwest breakdown before shelling out any money in your office pool.