For your Saturday convenience, we've removed weeknight games from this guide.
Saturday
| Time | Road | Home | TV | Streaming |
| Noon ET | Texas | No. 11 Kansas State | ESPN | ESPN3.com |
| Noon ET | Rutgers | No. 16 Nebraska | ESPN2 | ESPN3.com |
| Noon ET | UAB | Arkansas | SEC Network | ESPN3.com |
| Noon ET | Minnesota | Illinois | ESPNU | ESPN3.com |
| Noon ET | North Texas | Rice | FSN, ROOT | foxsports.com/foxsportsgo |
| Noon ET | Memphis | SMU | ESPNews | ESPN3.com |
| Noon ET | Maryland | Wisconsin | Big Ten Network | btn2go.com |
| 12:30 p.m. ET | North Carolina | Virginia | ACC Network | |
| 1 p.m. ET | Northern Illinois | Eastern Michigan | ESPN3.com | |
| 1 p.m. ET | San Jose State | Navy | CBSSN | |
| 2 p.m. ET | No. 25 UCLA | Colorado | Pac-12 Network | pac-12.com/live |
| 2 p.m. ET | Akron | Ball State | ESPN3.com | |
| 2 p.m. ET | Georgia Southern | Georgia State | ESPN3.com | |
| 2 p.m. ET | Massachusetts | Toledo | ESPN3.com | |
| 2 p.m. ET | Ohio | Western Michigan | ESPN3.com | |
| 2:30 p.m. ET | Kent State | Miami (Ohio) | ESPN3.com | |
| 3:30 p.m. ET | No. 1 Mississippi State | Kentucky | CBS | CBSSports.com |
| 3:30 p.m. ET | No. 22 West Virginia | Oklahoma State | ESPN | ESPN3.com |
| 3:30 p.m. ET | Texas Tech | No. 10 TCU | FOX | foxsports.com/foxsportsgo |
| 3:30 p.m. ET | Florida Atlantic | No. 23 Marshall | FS1 | foxsports.com/foxsportsgo |
| 3:30 p.m. ET | Michigan | No. 8 Michigan State | ABC | abc.go.com/watch-live |
| 3:30 p.m. ET | Central Michigan | Buffalo | ESPN3.com | |
| 3:30 p.m. ET | Georgia Tech | Pittsburgh | ESPNU | ESPN3.com |
| 3:30 p.m. ET | Louisiana Tech | Southern Miss | ASN, CSN | |
| 3:30 p.m. ET | Oregon State | Stanford | ESPN2 | ESPN3.com |
| 3:30 p.m. ET | Boston College | Wake Forest | RSN, ROOT | |
| 4 p.m. ET | Vanderbilt | Missouri | SEC Network | ESPN3.com |
| 4 p.m. ET | UNLV | Utah State | ESPNews | ESPN3.com |
| 4 p.m. ET | Old Dominion | Western Kentucky | conferenceusa.com | |
| 5 p.m. ET | Temple | UCF | CBSSN | |
| 6 p.m. ET | No. 15 Arizona | Washington State | Pac-12 Network | pac-12.com/live |
| 7 p.m. ET | Syracuse | No. 21 Clemson | ESPNU | ESPN3.com |
| 7 p.m. ET | Wyoming | Colorado State | ROOT | |
| 7 p.m. ET | UTEP | UTSA | Sinclair, ASN, CSN | |
| 7 p.m. ET | Texas State | ULM | ESPN3.com | |
| 7:15 p.m. ET | No. 3 Ole Miss | No. 24 LSU | ESPN | ESPN3.com |
| 7:30 p.m. ET | South Carolina | No. 5 Auburn | SEC Network | ESPN3.com |
| 7:30 p.m. ET | No. 4 Alabama | Tennessee | ESPN2 | ESPN3.com |
| 8 p.m. ET | No. 13 Ohio State | Penn State | ABC | abc.go.com/watch-live |
| 10 p.m. ET | No. 20 USC | No. 19 Utah | FS1 | foxsports.com/foxsportsgo |
| 10:45 p.m. ET | No. 14 Arizona State | Washington | ESPN | ESPN3.com |
| Midnight ET | Nevada | Hawaii | Oceanic | themw.com/#!/watch-live |
Early shift
Best option: Texas at No. 11 Kansas State
Spread: KSU -10
Read: Burnt Orange Nation, Bring On The Cats
The smoke settles. Kansas State brushes off its face, opens its eyes, and finds itself atop the Big 12 throne at 3-0 with wins over Oklahoma, Texas Tech, and Iowa State. Well, the OU win was a big deal, anyway. Texas is talented enough to hang with KSU, but the Longhorns have been in "baby steps" mode the entire season and haven't demonstrated the whole "execution" part nearly well enough to suggest they'll be topping the 'Cats here. Still, if pure, unadulterated chaos is what you want, you root for Texas to pull the upset.
Plan B: Rutgers at No. 16 Nebraska
Nebraska's the Big Ten West's best team virtually by default — there are some truly embarrassing losses haunting almost every other team in the division — and this might be the toughest left on the Huskers' schedule. Yes, Rutgers. And hey, that's 5-2 Rutgers to you, pal! Look for a huge day from Ameer Abdullah, especially if you're planning on seeing him in any contention for postseason plaudits in December.
Keep it in mind: Maryland at Wisconsin
Hey, Maryland's decent, sitting one win away from bowl eligibility, and while the Terps aren't going to threaten for the Big Ten East crown, they sure might disrupt the plans of Wisconsin and Heisman contender Melvin Gordon III. Look, it's the third-best game at noon. I don't know what more you were expecting.
In case of emergency: North Carolina at Virginia
This game's as "in case of emergency" as it gets. Still, there should be points by the bucketful, thanks to North Carolina's habit of letting both teams light up the scoreboard (average points scored by the losing team in UNC's seven games: 33.5). The best part is, a UNC win puts both teams at 2-2 in conference play and keeps the Coastal's "All 4-4 Everything" dream alive.
Middle shift
Best option: No. 1 Mississippi State at Kentucky
Spread: Mississippi State -13.5
Read: For Whom The Cowbell Tolls, A Sea Of Blue
Coming into the season, if you'd have seen this game atop the list of an afternoon slate, you'd probably think a sick joke was being played. But no! Mississippi State looks 100 percent legit, and Kentucky is 5-2 and controlling its own destiny in the SEC East race. Like, this is all happening in late October! We'd like to think an upset is possible, but this is the same UK defense that ceded 295 passing yards to human incompletion factory Jeff Driskel, so MSU QB Dak Prescott must be downright gleeful for the opportunity.
Plan B: No. 22 West Virginia at Oklahoma State
Bet you didn't think West Virginia would be the sole ranked team in this matchup two weeks ago, eh? The Mountaineers upset Baylor 41-27 last week in Morgantown, while OSU was throttled 42-9 by TCU. This one's a virtual toss-up, with the winner holding a 4-1 Big 12 record and the loser effectively out of conference championship contention. West Virginia's 2-1 away from Morgantown with a pair of three-point wins over rinky-dink competition and a 10-point loss to Bama, so Dana Holgorsen and crew have plenty to prove in hostile territory.
Keep it in mind: Michigan at No. 8 Michigan State
This is going to be a massacre, isn't it? Michigan's a horror show on its own, and MSU has reveled in crushing its (former) "big brother" in recent years. If Brady Hoke just wanders away from the sideline in the third quarter with Sparty up like 41-0, please understand he's not coming back, and it's not going to do any good to look for him. Just replace him and move on.
In case of emergency: Texas Tech at No. 10 TCU
Well, at least Kliff Kingsbury is still handsome, he'll tell himself while looking in the mirror after high-powered TCU napalms the living hell out of the Red Raider defense for 60 minutes.
Late shift
Best option: No. 3 Ole Miss at No. 24 LSU
Spread: Ole Miss -3.5
Read: Red Cup Rebellion, And The Valley Shook
Ole Miss is legit, right? The win over Alabama could've been a little fluky, but it was still a win over Alabama. The defense is allowing 10.6 points per game, and nobody outside of Bama has posed a serious threat to beat the Rebels. But man, this game is no sure thing. After a slow start, LSU has regained its footing and just might be the best two-loss team in the country. Les Miles' boys are back to 6-2 (2-2) with a devilish four-game slate to finish off the year: Ole Miss, Alabama, at Arkansas, at Texas A&M. Anything from 0-4 to 4-0 is possible. It's Les. The key in this one is if Leonard Fournette can get loose against that opportunistic Ole Miss defense.
Plan B: No. 20 USC at No. 19 Utah
Any concern as to whether Cody Kessler could thrive in the shadows of USC's previous great QBs was effectively answered with Kessler's record-setting seven-TD performance as USC demolished Colorado last week. Meanwhile, Utah hasn't been blowing out its power opponents, but the Utes have been winning pretty regularly all the same, and now they welcome the Trojans under the lights at Rice-Eccles Stadium. The betting lines suggest this one's a toss-up, and watching Kessler try to solve the Ute secondary should be a treat.
Keep it in mind: No. 4 Alabama at Tennessee
It's probably time to stop worrying about Alabama, which is to say worrying about Nick Saban, Lane Kiffin, Blake Sims, the defense, or whoever else you've been doubting as of late. The Tide erased Texas A&M, 59-0 (and could have hung 70+ on the Aggies if Saban were in a worse mood), and now set their sights on a rebuilding Tennessee as Bama keeps fighting for a spot in the Playoff. Don't think the committee has let Alabama off its radar for a moment.
In case of emergency: South Carolina at No. 5 Auburn, No. 13 Ohio State at Penn State, No. 14 Arizona State at Washington, Syracuse at No. 21 Clemson
The average line in this foursome is about 12, with only ASU-Washington in single digits (thanks to the unclear status of ASU QB Taylor Kelly). The numbers suggest at least one ranked team out of the group will be taken down, though much more than one is unlikely. So it's really about which conference you're repping. My advice is to root for the upset in the Pac-12. Let's get super weird with the late-night football.