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49ers Vs. Lions: Alex Smith Fumbles On First Play

If the San Francisco 49ers' first play from scrimmage is any indication, it could be a long day for the surprise 4-1 team. Alex Smith was stripped from behind by Kyle Vanden Bosch, setting the Detroit Lions up on the 49ers 32-yard line. They would eventually turn it into a 3-0 lead, which has since grown to 10-0.