The Chiefs will sit quarterback Ricky Stanzi, wide receiver Devon Wylie, defensive back Tysyn Hartman, linebacker Bryan Kehl, center Bryan Mattison, defensive end Glenn Dorsey and tight end Steve Maneri.
Oakland will be without quarterback Terrelle Pryor, running back Taiwan Jones, cornerback Shawntae Spencer, linebacker Travis Goethel, guard Lucas Nix, defensive end Jack Crawford and offensive tackle Khalif Barnes.
Both teams have struggled in the first half of the season, but a weak division has allowed the Raiders and Chiefs to remain in playoff contention. Kansas City is just two games out of first place, despite winning just once on the season. Oakland got a win last week and now sits just one game behind the Chargers and Broncos for first place.