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Week 3 NFL preview: Colts vs. 49ers

Colts-Niners is the game of the week: Andrew Luck and Coby Fleener return to northern California to face off against their coach at Stanford, Jim Harbaugh. Trent Richardson makes his Colts debut. And San Francisco looks to put the hurt on Indy after struggling in primetime against Seattle.

The 49ers are riddled with injuries coming off a beatdown at the hands of the Seahawks last week and will be looking to bounce back against an unexpectedly improved Colts team. In a bewildering move that could only have been made by the masochistic Browns, Trent Richardson suddenly ends up alongside Andrew Luck, reuniting a pair that shared the green room for a very brief period of time during the 2012 NFL Draft.