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Colts vs. Jaguars 2016 picks and predictions: No clear-cut favorite for the AFC South matchup in London

Indianapolis and Jacksonville head over the pond to Wembley Stadium in this Week 4 matchup.

Both the Indianapolis Colts and the Jacksonville Jaguars look to gain some early-season footing as they travel across the pond for Sunday’s matchup at Wembley Stadium in London, England.

The Colts come into the game with a 1-2 record after last weekend’s 26-22 victory over the San Diego Chargers. This weekend’s matchup marks the team’s first-ever game played in London. It’s a must-win against a fellow opponent in the AFC South, where the team finds itself in a second-place tie with the Tennessee Titans.

Jacksonville, the home team for Sunday’s game, will be hosting a London matchup for the fourth consecutive season. The Jaguars find themselves at 0-3 after last week’s 19-17 home loss to the Baltimore Ravens, leaving the team all alone at the bottom of their division.

The Colts hold a 21-9 series lead over the Jaguars and have won six of their last seven matchups. Colts head coach Chuck Pagano boasts a 6-2 record against the Jaguars, while Jacksonville's Gus Bradley is just 1-5 against Indianapolis.

In his fourth season with the team, Gus Bradley’s seat is growing increasingly hot with each loss. If the Jaguars are unable to pick up a victory soon, Bradley may find himself without a job.

The experts are mostly split on whether the Jaguars can get Bradley a much-needed win on Sunday. On the eight-man panel at CBS Sports, the Colts are favored by a 6-2 tally.  Of the five ESPN experts who have submitted their picks, three out of the five think Indianapolis will get the win over Jacksonville.

Here at SB Nation, the predictions are right down the middle:

Game RVB Stephen White Thomas George Jeanna Thomas Adam Stites Tyler Tynes Louis Bien Joel Thorman Fooch OddsShark computer

That’s five for the Colts, and five for the Jaguars. See who comes out on top this Sunday at 9:30 a.m. ET, when the game will be available for viewing on CBS.