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NFL odds: opening spreads for Week 11 betting

Seattle at Kansas City is one of many interesting games on this week's NFL betting card.

The Kansas City Chiefs are 5-2 SU and 6-1 ATS in their last seven games against the defending champion Seattle Seahawks. Kansas City hopes to pick up a statement win hosting the Seahawks Sunday.

Seattle is a 1.5-point underdog Sunday, according to sportsbooks monitored by OddsShark.com. The Seahawks are just 2-4 SU in their last six games as a road underdog. Kansas City is 4-0 SU and ATS over its last four games overall and 6-1 SU and ATS over its last seven.

Buffalo at Miami Thursday night will be an important game for both teams' playoff chances as the Bills and Dolphins both currently have a 5-4 SU record. The UNDER is 7-2 in the last nine games between these two AFC East rivals and 3-1 in Buffalo's last four games as a road underdog and Miami's last four games as a home favorite. Miami is favored by five points at home.

[ See live NFL odds updates on lines and totals and trends on every matchup ]

Fresh off a road upset against the New Orleans Saints, the San Francisco 49ers are back on the road Sunday against the New York Giants. New York is 0-4 SU and ATS over its last four games with four-straight double-digit losses. The Giants are just 2-11 SU in their last 13 games as a home underdog, and they'll be one again Sunday going off at +4 at Bovada.

The Detroit Lions visit the Arizona Cardinals Sunday in a battle between two of the NFC's hottest teams. Detroit is 4-0 SU over its last four games and 7-2 SU so far this season while the Cardinals are a perfect 5-0 SU and ATS over their last five games and 8-1 SU on the season.

Arizona is a 2-point favorite at home with Drew Stanton set to start for the injured Carson Palmer.

Indianapolis is a 2.5-point favorite Sunday night hosting the New England Patriots. New England is 5-0 SU and 4-1 ATS over its last five games and Indianapolis is 6-1 SU and ATS over its last seven. This one should be an exciting game between two of the NFL's best quarterbacks and offenses.