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Villanova vs. Kansas 2016 odds: Favored Jayhawks surging into game against Wildcats

The top two seeds in the South Region meet on Saturday as favored No. 1 Kansas takes on underdog No. 2 Villanova in the Elite Eight.

Jamie Rhodes-USA TODAY Sports

With another blowout win in the Sweet 16, the Kansas Jayhawks are now 17-0 straight up and 14-3 against the spread in their last 17 games. The Jayhawks will try to keep the train rolling in the Elite Eight this Saturday against a tough opponent in the Villanova Wildcats.

Kansas is a 2.5-point betting favorite in Saturday's matchup at sportsbooks monitored by OddsShark.com. In their last six games as a favorite of 5.5 points or fewer, the Jayhawks are a perfect 6-0 SU and ATS.

The betting line on the Jayhawks' Sweet 16 game against Maryland closed with Kansas as a 5.5-point favorite, a spread that was comfortably covered in the team's 79-63 win. The Jayhawks were only up two points at the half, but they made the necessary adjustments and won the second half by 14 points.

The win highlighted Kansas' strengths on defense and in rebounding, and earned the Jayhawks their first trip to the Elite Eight since 2012.

The Jayhawks have advanced to the Elite Eight five times since 2004. Kansas is 2-3 SU and 1-4 ATS in those games per the OddsShark College Basketball Database.

The Villanova Wildcats are built to live or die by the three-ball, and so far in March Madness they've been living well. The Wildcats are 3-0 SU and ATS through tournament play so far, beating their opponents by an average score of 24 points per game and shooting 53.2% from behind the arc on 62 attempts.

Villanova had a hot shooting night in dropping 92 points in its 92-69 win over No. 3 Miami, and will need another strong performance on Saturday to upset Kansas.

Saturday's total is set at 145.5 points. The OVER is 10-2 in Villanova's last 12 games overall.

Kansas is arguably the deepest and most versatile team in the nation, making the Jayhawks an understandable odds-on favorite to win the NCAA Tournament. But in the one-and-done format that makes March Madness famous, all it takes is one red-hot team to knock off even the biggest of favorites, and Villanova certainly has the talent and the current form to be a threat to do just that.